CJC-no DAC / Ipamorelin Blend – 5mg/5mg

CJC-1295 (No DAC) / Ipamorelin Peptide Blend

For Research Use Only. Not for human or veterinary use.

CJC-1295 (No DAC) / Ipamorelin is a research peptide blend that combines two growth hormone secretagogues commonly studied for their effects on endogenous growth hormone signaling. CJC-1295 (No DAC) is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH) designed to support pulsatile growth hormone release, while Ipamorelin is a selective growth hormone secretagogue that acts through ghrelin receptor pathways. Researchers frequently investigate this combination for its potential effects on growth hormone secretion, metabolic regulation, and recovery-related signaling pathways.

Mechanism of Action

Research suggests CJC-1295 (No DAC) stimulates growth hormone release through activation of GHRH receptors located on pituitary somatotroph cells. Due to its shorter duration of activity compared to DAC-modified variants, it is commonly investigated for its ability to support natural pulsatile growth hormone secretion patterns.

Ipamorelin functions as a selective growth hormone secretagogue that interacts with growth hormone secretagogue receptors (GHS-R), stimulating endogenous growth hormone release. Experimental studies suggest the combination of CJC-1295 (No DAC) and Ipamorelin may provide complementary stimulation of growth hormone pathways through distinct receptor mechanisms.

Research Applications

Studies have explored CJC-1295 (No DAC) and Ipamorelin in several areas of experimental research:

• Growth Hormone Secretion Research: Investigated for effects on endogenous growth hormone release and pulsatile GH signaling.
• Metabolic Function Research: Studied for potential involvement in energy regulation, nutrient utilization, and metabolic homeostasis.
• Body Composition Research: Experimental models have explored associations with lean tissue maintenance and adipose tissue metabolism.
• Recovery and Tissue Repair Research: Growth hormone-related pathways are frequently investigated for their role in tissue maintenance, cellular recovery, and physiological adaptation.
• Sleep and Neuroendocrine Research: Researchers have examined growth hormone secretagogues for their relationship to sleep-associated hormone release patterns and neuroendocrine signaling.

Chemical Information

CJC-1295 (No DAC)

• Classification: Synthetic Growth Hormone-Releasing Hormone (GHRH) Analog
• Molecular formula: C152H252N44O42
• Molecular weight: 3367.9 g/mol

Ipamorelin

• Molecular Formula: C38H49N9O5
• Molecular Weight: ~711.86 g/mol

Blend Classification

Multi-Peptide Growth Hormone Secretagogue Research Blend

References

• https://academic.oup.com/jcem/article/91/3/799/2843375
• https://academic.oup.com/jcem/article/91/7/2452/2656286
• https://pubmed.ncbi.nlm.nih.gov/9849822/
• https://pubmed.ncbi.nlm.nih.gov/8784072/
• https://pubmed.ncbi.nlm.nih.gov/10534165/
• https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/cjc-1295